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Find out more about the project, the specific objectives and the institutions involved. Acerca de About the Project Biological systems research focusing on elucidating plant stress mechanisms and signaling pathways is important for developing resistant cultivars in a climate change scenario. Pathogen attacks and abiotic stresses such as water deficit are essential during plant development, and the identification of genes and molecules, which regulate resistance responses, are critical to develop crop cultivars capable of doing in the face of these stresses. In association with abiotic stresses, plants must also defend themselves against pest’s attacks, including fungi, bacteria, insect pests, and nematodes. Insect-pests comprise the most serious factor affecting productivity losses in the Brazilian agribusiness. Losses in soybean, cotton, and corn caused by the caterpillars Helicoverpa armigera , Spodoptera frugiperda , and phytonematodes constitute the most critical phytosanitary problem in terms of competitiveness for the commodities production and exportation. Faced with scenario cases involving plant resistance breakdown, environmental association of biotic and abiotic stresses, fewer characterized and introgressed genes, and higher complexity of plant responses have been reported. All these reports demonstrate the importance of the research towards the identification of genes/molecules involved in pest resistance and water deficit responses. In this context, the National Institute of Science and Technology, PlantStress Biotech INCT, integrates various Brazilian research groups and international partners, experts in plant physiology, transcriptomic, epigenetic, proteomic, bioinformatic and functional genomics analyses. The integrative research group represents a multidisciplinary and multi-institutional network with national and international excellence to generate innovative biotechnologies applied to corn, soybean and cotton focused on the tolerance to deficit hydric and pest control (Meloidogyne spp, H. armigera and S. frugiperda ). The project includes bioprospection, isolation, characterization, and functional validation of genes/molecules involved in plant pest resistance and drought tolerance. The PlantStress Biotech INCT action comprises: Prospection for genes and molecules involved in resistance/tolerance to specific and combined stresses in native plants and resistant/tolerant contrasting genotypes, through the elucidation of the stress mechanisms and signaling pathways; Prospection for genes and molecules involved in the defense and parasitism of target pests; Search for promoters responsive to pests and water deficit, and small RNAs involved in the regulation of target genes; Use different strategies (gene/molecules overexpression or gene silencing) for biological functional validation in model systems; Developing of new nanoencapsulated insecticides/nematicides from validated molecules; Developing of biotechnological products (concept proof) in GM crop plants (cotton, soybean, and maize); Evaluation of developed GM crop plants in simulated field experiments. The biotech assets generated will be applied to the development of biotechnology products, including nanobioinsecticides and genetically modified crops (soybean, maize, and cotton) against biotic and abiotic stresses. In addition to the biotech assets obtained and characterized in this project, an understanding of molecular and physiological factors related to drought tolerance and their interaction with pests and other environmental stresses will contribute to prevent, unravel and adapt to climatic changes. Alongside its scientific agenda, the PlantStress Biotech INCT group, formed by researchers from five Embrapa units and five Federal Universities (UnB, UFRJ, UFRGS, UFC, and UFPel), and collaborators from the public and private sectors, concentrate their efforts on training students and professionals in different and update approaches involving biotechnology, genomics, and bioinformatics. Actions will also strengthen joint action and the internationalization of undergraduate and graduate training engaged in PlantStress Biotech INCT research, and to increase the visibility and international insertion of its teams. The PlantStress Biotech INCT network focuses not only on the generation of biotech assets applied to drought and pests in soybean, cotton, and maize but also on other important agronomic traits (seed and fruit quality, an increase of biomass and nutritional value, among other) and in other crops important for Brazilian agribusiness.

Learn more about AL07, its main goals within the project and meet the laboratory's work team. AL 07 - Insects and Nematodes: Breeding and Bioassays Laboratory Activities - PlantStress Biotech INCT Organize, maintain and share an in vivo bank of the innovation assets obtained in the project shared by INCT members. Leonardo Lima Pepino de Macedo Team Leader Dr. Leonardo is undergraduated in Biological Sciences from the Federal University of Rio Grande do Norte (2005). He holds a master's degree in Biochemistry from the Federal University of Rio Grande do Norte (2007), and a doctorate's degree in Genomic Science and Biotechnology from the Catholic University of Brasília (2012). He has experience in Biochemistry and Molecular Biology, with expertise in the following topics: cloning and expression of proteins in heterologous systems; bioprospecting of proteins with entomotoxic activity (vicillins, lectins, proteinase inhibitors and Cry toxins) aiming at the control of dipterous, lepidopteran and coleopteran insects; and development of gene silencing strategies via interfering RNA (RNAi) for the control of insect pests. Contact Leonardo Lima Pepino de Macedo EMBRAPA Genetic Resources and Biotechnology W5 Norte Avenue (end) - P.O. Box 02372 - Postal Code 70770-917 - Brasília, DF - Brazil E-mail: leonardo.lima@embrapa.br Phone number:+55 61 3448-4705

Discover how we are turning curiosity into innovation, fostering excellence in scientific research. News 13/02/2025 8th Brazilian Biotechnology Congress We are honored to invite you to participate in the 8th Brazilian Biotechnology Congress, which will be held from October 19 to 22, 2025, in Natal, RN, Brazil. Read More 28/01/2024 INCT PlantStress Biotech research shines at PAG32. INCT PlantStress Biotech research shines at the Plant and Animal Genome Conference (PAG32) in San Diego, January 10-15th, USA. Read More 28/01/2024 O Tomate Roxo GM - rico em antocioninas Palestra destaque no evento PAG 32 de Cathie Martin, responsável pela produção do Tomate Roxo Geneticamente Modificado, que aumenta os benefícios à saúde e enriquece os efeitos nutritivos. Read More 15/10/2024 INCT PlantStress Biotech: Disseminating Knowledge in Educational Institutions Dr. Ana Cristina Miranda Brasileiro from Embrapa – Cenargen has shared knowledge and technological innovations from INCT PlantStress Biotech with society. She participates in science education programs for elementary and high school students in the Distrito Federal (DF). Read More 15/10/2024 Advances in Research from UFRJ and Embrapa on Coffee Gene that Increases Drought Resistance in Soybeans and Cotton The research was conducted by the Molecular Genetics and Plant Biotechnology Laboratory at UFRJ, led by Professor Márcio Alves-Ferreira, in collaboration with the team from Embrapa Cenargen, coordinated by researcher M. Fatima Grossi de Sa. Read More 15/10/2024 INCT PlantStress Biotech’s Participation in the International Congress of Nematology (ICN) in Antibes Juan-Les-Pins, France Professor Robert Miller (UnB), a member of the INCT PlantStress Biotech, participated in the 7th International Congress of Nematology (ICN), between the 1st and 6th of May 2022. Read More 13/02/2025 8th Brazilian Biotechnology Congress We are honored to invite you to participate in the 8th Brazilian Biotechnology Congress, which will be held from October 19 to 22, 2025, in Natal, RN, Brazil. Read More 28/01/2024 INCT PlantStress Biotech research shines at PAG32. INCT PlantStress Biotech research shines at the Plant and Animal Genome Conference (PAG32) in San Diego, January 10-15th, USA. Read More 28/01/2024 O Tomate Roxo GM - rico em antocioninas Palestra destaque no evento PAG 32 de Cathie Martin, responsável pela produção do Tomate Roxo Geneticamente Modificado, que aumenta os benefícios à saúde e enriquece os efeitos nutritivos. Read More 15/10/2024 INCT PlantStress Biotech: Disseminating Knowledge in Educational Institutions Dr. Ana Cristina Miranda Brasileiro from Embrapa – Cenargen has shared knowledge and technological innovations from INCT PlantStress Biotech with society. She participates in science education programs for elementary and high school students in the Distrito Federal (DF). Read More 15/10/2024 Advances in Research from UFRJ and Embrapa on Coffee Gene that Increases Drought Resistance in Soybeans and Cotton The research was conducted by the Molecular Genetics and Plant Biotechnology Laboratory at UFRJ, led by Professor Márcio Alves-Ferreira, in collaboration with the team from Embrapa Cenargen, coordinated by researcher M. Fatima Grossi de Sa. Read More 15/10/2024 INCT PlantStress Biotech’s Participation in the International Congress of Nematology (ICN) in Antibes Juan-Les-Pins, France Professor Robert Miller (UnB), a member of the INCT PlantStress Biotech, participated in the 7th International Congress of Nematology (ICN), between the 1st and 6th of May 2022. Read More

BioIberoamérica 2024 will take place from 3-6 September 2024 in Monterrey, Mexico. The event proposes promote the exchange of experiences among the different actors of the biotechnology sector, to identify the demands of research, innovation and technology transfer. < Back 4th Bio Iberoamérica 3-6 September 2024 BioIberoamérica 2024 will take place from 3-6 September 2024 in Monterrey, one of the most dynamic cities in the world, located in the northeast of Mexico, a region bordering the USA, characterized by a dynamic strategy for economics, social development, innovative, with educative institutions recognized globally and a great biotechnological sector including the main biotech cluster in Mexico. The event proposes a broad program of activities with oral presentations, poster sessions, round tables, workshops, and parallel technical sessions, to bring together experts to promote the exchange of experiences among the different actors of the biotechnology sector, to identify the demands of research, innovation and technology transfer. The BioIberoamerica congress has been organized successfully in Iberoamerican cities such as Salamanca, Spain in 2016; Brasilia, Brazil in 2018; and Braga, Portugal in 2022, mainly due to the collaborative effort of biotechnological associations from Brazil, Mexico, Portugal, and Spain. The congress is been organized on its 4th edition by the Universidad Autónoma de Coahuila, the Tecnológico de Monterrey, the Mexican Association of Food Science (AMECA), and Bioprocessing MxLatam, a Mexican and Latin-American biotechnology network. Bioiberoamerica has become one of the leading biotech events in Iberoamerica, being the perfect setting for forging new partnerships, scientific and academic collaboration, and strengthening existing business relationships in the biotechnological global sector. BioIberoamerica 2024 will bring together more than 500 participants working in health, sustainable agri-food, and climate change solutions and biotechnological innovations. The event is attended by professionals, students, exhibitors, and investors. Visit: http://bioiberoamerica2024.uadec.mx/

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